Anti-Human USP14 Aptamer(Cat#: CTMM-0124-LH45)
This product is an aptamer which binds to Human USP14 domain with a high affinity.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
USP14 |
| Alternative Names |
Ubiquitin Specific Peptidase 14; TGT; Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase); Ubiquitin Specific Protease 14 (TRNA-Guanine Transglycosylase); Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; Ubp6; TRNA-Guanine Transglycosylase, 60-KD Subunit; Ubiquitin-Specific Processing Protease 14; Ubiquitin-Specific-Processing Protease 14; Ubiquitin Thiolesterase 14; EC 3.4.19.12; EC 3.1.2.15; UBP6 |
| Gene ID |
9097 |
| UniProt ID |
P54578 |
| Target Overview |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mouse with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Type |
RNA |
| Species Reactivity |
Human |
| Length |
50-100 nt |
| Binding Conditions/Buffer |
30mM Tris-HCl, 150mM NaCl, 1.5mM MgCl2, 2mM DTT, and 1% (w/v) BSA, pH=7.5 |
| GC Content |
54.74% |
| Molecular Weight |
30329.1 g/mole |
| nmoles/OD260 |
0.875 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
