This product is an aptamer which binds to the Neopterin with a high affinity.
Target Category | Small Organic |
Target | Neopterin |
Alternative Names | N/A |
Gene ID | N/A |
UniProt ID | N/A |
Target Overview | Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation. |
Chemical Modification | DNA |
Length | 20-40 nt |
Affinity (Kd) | N/A |
Binding Conditions/Buffer | 5 mM MgCl₂, 10 mM TRIS buffer, 100 mM KCl, and 100 mM NaCl |
GC Content | 33 |
Molecular Weight | 12227 |
Extinction Coefficient | 354200 |
nmoles/OD260 | 2.629 |