Anti-PTGDR2 Aptamer(Cat#: CTApt-727)
This product is an aptamer which binds to the PTGDR2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
PTGDR2 |
| Alternative Names |
Prostaglandin D2 Receptor 2; CRTH2; Chemoattractant Receptor Homologous Molecule Expressed On T Helper Type 2 Cells; G-Protein Coupled Receptor 44; CD294; GPR44; DL1R; DP2; Chemoattractant Receptor-Homologous Molecule Expressed On TH2 Cells; Chemoattractant Receptor-Homologous Molecule Expressed On Th2 Cells; Putative G-Protein Coupled Receptor 44; G Protein-Coupled Receptor 44; CD294 Antigen; PTGDR2 |
| Gene ID |
4502 |
| UniProt ID |
Q9Y5Y4 |
| Target Overview |
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
