Anti-TNFAIP3 Aptamer(Cat#: CTApt-2355)
This product is an aptamer which binds to the TNFAIP3 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
TNFAIP3 |
| Alternative Names |
TNF Alpha Induced Protein 3; OTUD7C; Tumor Necrosis Factor Alpha-Induced Protein 3; OTU Domain-Containing Protein 7C; Putative DNA-Binding Protein A20; Zinc Finger Protein A20; A20; Tumor Necrosis Factor, Alpha-Induced Protein 3; Tumor Necrosis Factor, Alpha Induced Protein 3; Tumor Necrosis Factor Inducible Protein A20; TNF Alpha-Induced Protein 3; EC 3.4.19.12; EC 2.3.2.- ; TNFA1P2; TNFAIP3; AISBL |
| Gene ID |
7128 |
| UniProt ID |
P21580 |
| Target Overview |
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
