Anti-TNFSF13B aptamer(Cat#: CTApt-1848)

This product is an aptamer which binds to the TNFSF13B with an affinity of 1nM~1μM.

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3’ Modification
 
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Summary

Specifications
Target Category Protein
Target TNFSF13B
Alternative Names TNF Superfamily Member 13b; B-Cell-Activating Factor; TALL-1; TALL1; BAFF; BLYS; Tumor Necrosis Factor (Ligand) Superfamily, Member 13b; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNF And ApoL-Related Leukocyte Expressed Ligand 1; Dendritic Cell-Derived TNF-Like Molecule; TNF Homolog That Activates Apoptosis; B-Lymphocyte Stimulator; TNFSF20; CD257; THANK; ZTNF4; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; TNF- And APOL-Related Leukocyte Expressed Ligand 1; Tumor Necrosis Factor Superfamily Member 13b; Epididymis Secretory Sperm Binding Protein; Tumor Necrosis Factor-Like Protein ZTNF4; Tumor Necrosis Factor Ligand 7A; ApoL Related Ligand TALL-1; B Lymphocyte Stimulator; CD257 Antigen; Delta4 BAFF; Delta BAFF; TNFSF13B; TNLG7A; BLyS; DTL
Gene ID 10673
UniProt ID Q9Y275
Target Overview The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Chemical Modification DNA/RNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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