Anti-XDH Aptamer(Cat#: CTApt-856)
This product is an aptamer which binds to the XDH with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
XDH |
| Alternative Names |
Xanthine Dehydrogenase; Xanthine Dehydrogenase/Oxidase; XOR; XO; Xanthine Oxidoreductase; Xanthene Dehydrogenase; EC 1.17.1.4; EC 1.7.2.2; XAN1; XDHA; XDH |
| Gene ID |
7498 |
| UniProt ID |
P47989 |
| Target Overview |
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
