Mouse Anti-Human CD59 Monoclonal Antibody (CTJS-327) [PE](Cat#: CTA-709)
This product is a conjugated anti-Human MAC-inhibitory protein (CD59) Monoclonal antibody (CTJS-327) generated from the Mouse. The antibody can be used for FC.
Summary
Related Products & Services
Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-327 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Mouse pre-B tumour cells |
| Species Reactivity |
Human |
| Applications |
FC |
| Application Notes |
FC: 1 µg/10^6 cells
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human MAC-inhibitory protein (CD59). |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
PE |
| Format |
Liquid |
| Size |
50 µg |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
CD59 |
| Alternative Names |
CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
| Gene ID |
966 |
| UniProt ID |
P13987 |
Information
| Introduction |
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
