Mouse Anti-Human Complement Factor Bb Monoclonal Antibody (CTJS-602)(Cat#: CTA-129)
This product is an unconjugated anti-Human Complement Factor Bb Monoclonal antibody (CTJS-602) generated from the Mouse. The antibody can be used for WB; ELISA.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-602 |
| Host Animal |
Mouse |
| Isotype |
IgG1κ |
| Immunogen |
Complement factor B purified from human plasma and adsorbed to aluminum hydroxide gel |
| Species Reactivity |
Human |
| Applications |
WB; ELISA |
| Application Notes |
WB: 1:100-1:2000
ELISA: 1:100-1:2000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with the Bb fragment of human factor B. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
25; 100 µL |
| Storage |
Store at 4°C. Do not freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
Factor Bb |
| Alternative Names |
Complement Factor Bb; Complement Factor Bb fragment; Factor Bb fragment; CF Bb |
| Gene ID |
629 |
| UniProt ID |
P00751 |
Information
| Introduction |
Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
