Anti-GRP78 (clone SAM-6Z) SynExpress C-G-I10-K Modified CD8+ T cells

CAT#: ITS-1224-CR1075
Clone: SAM-6Z
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-GFP-IL-10-KpnI
Carrier Type: AAV
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GRP78 (clone SAM-6Z). We employs the AAV (CMV-GFP-IL-10-KpnI) vector components and the SynExpress system of the Exons Inversion/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GRP78
Clone
SAM-6Z
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
KpnI
Gene Modification
Inversion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Target
GRP78
Alternative Names
HSPA5; BIP; GRP78; HEL-S-89n; MIF2; Binding immunoglobulin protein; heat shock protein family A (Hsp70) member 5; GRP78/Bip
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
3309(Human); 14828(Mouse); 25617(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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