Anti-MUC16 (clone VK-8P) SynExpress SV-mCh-I4-X Modified CD8+ T cells

CAT#: ITS-1224-CR1267
Clone: VK-8P
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: SV40-mCherry-IL-4-XbaI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target MUC16 (clone VK-8P). We employs the Lentivirus (SV40-mCherry-IL-4-XbaI) vector components and the SynExpress system of the Exons Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
MUC16
Clone
VK-8P
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
SV40
Effector Gene
IL-4
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
Exons
Carrier Type
Lentivirus
Transformation Accuracy
0.86
Cell Culture
3D Culture
Target
MUC16
Alternative Names
Mucin-16; MUC-16
Gene ID
Q8WXI7(Human)
UniProt ID
94025(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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