Anti-CCL2 Aptamer(Cat#: CTApt-798)
This product is an aptamer which binds to the CCL2 with an affinity of 1nM~1μM.
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Summary
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Specifications
| Target Category |
Protein |
| Target |
CCL2 |
| Alternative Names |
C-C Motif Chemokine Ligand 2; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE; MCP-1; HC11; MCAF; MCP1; Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je); Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Monocyte Chemoattractant Protein-1; Chemokine (C-C Motif) Ligand 2; Monocyte Chemotactic Protein 1; Small-Inducible Cytokine A2; C-C Motif Chemokine 2; GDCF-2; SMC-CF; SCYA2; Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je; Monocyte Chemoattractant Protein 1; HSMCR30; MGC9434; CCL2 |
| Gene ID |
6347 |
| UniProt ID |
P13500 |
| Target Overview |
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
