CD59 Blocking Peptide(Cat#: CTD-148)
This product is a synthetic peptide that used for blocking the activity of human CD59 antibody.
Summary
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Specifications
| Purity |
>90% |
| Pack Size |
50 µg |
| Format |
Liquid |
| Conjugate |
Unconjugated |
| Species Reactivity |
Human |
| Applications |
Blocking |
| Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
| Introduction |
CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
