CH50 Functional Test Kit(Cat#: CTK-907)
This product is a functional test kit to determine the activity of classical complement pathway based on the erythrocytes hemolysis assay. It is available for the sample of plasma or serum of several species, such as human,mouse, rat, guinea pig, bovine, hamster, swine, sheep, monkey. This kit also can be used to screen oe assess the pharmaceutical effect of complement therapeutic inhibitors or activators.
Summary
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Specifications
| Assay Type |
Complement Functional Assay |
| Species Reactivity |
Mul-species (human,mouse, rat, guinea pig, bovine, hamster, swine, sheep, monkey) |
| Applications |
Complement functional test |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
The CH50 is usually used to represent the total complement activity, or screen the activation/deficiency of the classical complement pathway. The CH50 test is based on the capacity of a serum to lyse sheep red blood cells (SRBC) coated with anti-sheep antibodies. When coated-antibody-SRBC complex are incubated with test serum, the classical pathway of complement is activated leading to SRBC hemolysis. The degree of hemolysis is related to the content and function of complement components in serum. As the complement content is positively correlated with the degree of hemolysis, not linearly, but in S-curve, the middle part of the reaction curve, i.e. 50% hemolysis (CH50), is usually taken as the end point. If a complement component is deficient or not activated, the membrane attack complex will not be formed, and no hemolysis can be observed. |
Customer Review
I'm giving this kit a top star rating
Excellent
As a regular user, I can say that this kit is very efficient and has dependable results. It definitely meets all my requirements for my experiments.
It is proving to be invaluable to our experiments
Excellent
I found the kit a bit complicated to use initially but after a couple of tries, I found it easier and efficient. It's worth the price, provides consistent, reproducible results. It greatly helped in facilitating our experiments.
I would highly recommend this kit for lab analysis
Excellent
Our lab techs were really satisfied with the CH50 functional test kit. The product did not disappoint and worked flawlessly, providing consistency in results. The testing process was smoother and quicker with the kit.
The kit is a happy composition of price, value, and functionality
Excellent
Easy to use, accurate results, and excellent value for money. What more could you ask for in a test kit?
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
