Complement C3 Immunizing Peptide-3(Cat#: CTD-037)
This product is a synthetic peptide that used as an immunogen for the generation of alpha 2 Macroglobulin antibody.
Summary
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Specifications
| Purity |
>90% |
| Pack Size |
100 μg |
| Format |
Lyophilized |
| Conjugate |
Unconjugated |
| Applications |
Immunogen |
| Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
| Introduction |
Complement C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
