CR1 Immunizing Peptide-1(Cat#: CTD-130)
This product is a synthetic peptide that used as an immunogen for the generation of human, mouse and rat Complement Receptor 1 antibody.
Summary
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Specifications
| Purity |
>90% |
| Pack Size |
1 mg |
| Format |
Lyophilized |
| Conjugate |
Unconjugated |
| Species Reactivity |
Human; Mouse; Rat |
| Applications |
Immunogen |
| Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
| Introduction |
Complement receptor type 1 ia a membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells. It acts as a receptor for Epstein-Barr virus in microbial infection. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
