Encoded by the CFP (complement factor properdin) gene in humans, properdin is a plasma glycoprotein with the ability to activate the complement system of the innate immune system. By binding to bacterial cell walls and dying human cells, properdin can form an attack complex that causes cell lysis. Here, Creative Biolabs describes the novel protocols to separate the different properdin oligomers in plasma using gel filtration or cation exchange.
Human CFP Purification Protocol
Fig.1 Flow chart of the human CFP purification protocol. (Creative Biolabs)
With our well-established platforms, the experienced scientists here at Creative Biolabs are dedicated to assisting in the field of human complement system research. We have developed a variety of products and services for our clients all over the world. We are confident in meeting the specific need of each customer with the best project design.
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