This product is an ELISA kit for the determination of Human Complement C2 in the samples of Serum, Plasma, Tissue Homogenate. It is highly sensitive and available for the detection of Human Complement C2 as low as 2.7 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 2.7 ng/mL (7.8-500 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | C2 |
Cross Reactivity | No significant cross-reactions have been observed between Human Complement C2 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | Complement C2 is a part of the classical pathway of the complement system, which is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. C2 is a major histocompatibility complex class-III protein. Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b. |