This product is an unconjugated anti-Human Complement C4BPB Monoclonal antibody (CTJS-385) generated from the Mouse. The antibody can be used for WB, IP, IF, ELISA.
Clonality | Monoclonal |
Clone | CTJS-385 |
Host Animal | Mouse |
Isotype | IgG2b κ |
Immunogen | Recombinant human C4BPB, a.a. 82-252 |
Species Reactivity | Human |
Applications | WB; IP; IF; ELISA |
Application Notes | WB: 1:100 - 1:1000 IP: 1-2 µg/mL IF: 1:50-1:500 ELISA: 1:30-1:3000 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human Complement C4BPB. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 200 µg |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | C4BPB |
Alternative Names | Complement Component 4 Binding Protein Beta C4b-Binding Protein Beta Chain Complement Component 4 Binding Protein, Beta Chain Complement Component 4-Binding Protein, Beta C4b Binding Protein, Beta Chain C4BPB C4BP |
Gene ID | 725 |
UniProt ID | P20851 |
Introduction | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |