This product is an unconjugated anti-Human Complement C8 Monoclonal antibody (CTJS-100) generated from the Mouse. The antibody can be used for WB; ELISA; FC; IHC.
Clonality | Monoclonal |
Clone | CTJS-100 |
Host Animal | Mouse |
Isotype | IgG1 |
Immunogen | Purified human C8 |
Species Reactivity | Human |
Applications | WB; ELISA; FC; IHC |
Application Notes | WB: 1:100-1:2000 ELISA: 1:100-1:2000 FC: 1:10-1:1000 IHC: 1:10-1:500 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human complement C8. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Liquid |
Size | 50 µg |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Type | Primary Antibody |
Target Name | C8 |
Alternative Names | Complement C8; Complement Component C8; Complement Component 8; C8 |
Gene ID | 731 |
UniProt ID | P07357 |
Introduction | C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. C8A inserts into the target membrane, but does not form pores by itself. |