Mouse Anti-Human CR1 Monoclonal Antibody (CTJS-707) [Alexa Fluor® 790](Cat#: CTA-782)
This product is a conjugated anti-Human CR1 Monoclonal antibody (CTJS-707) generated from the Mouse. The antibody can be used for WB, IF, FC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-707 |
| Host Animal |
Mouse |
| Isotype |
IgG1 κ |
| Immunogen |
Human monocytes |
| Species Reactivity |
Human; Primate |
| Applications |
WB; IF; FC |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human and Primate CR1. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Alexa Fluor® 790 |
| Format |
Liquid |
| Size |
200 µg |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
CR1 |
| Alternative Names |
Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); Complement Receptor Type 1; C3b/C4b Receptor ; CD35 Antigen; C3BR; CD35; Complement Component 3b/4b Receptor 1; Knops Blood Group Antigen; Complement Receptor 1; C3-Binding Protein; C4BR; CR1 |
| Gene ID |
1378 |
| UniProt ID |
P17927 |
Information
| Introduction |
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells.
Acts as a receptor for Epstein-Barr virus. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
