Mouse Anti-Human Factor B Ba Monoclonal Antibody (CTJS-667)(Cat#: CTA-576)
This product is an unconjugated anti-Human Complement Factor B Ba Monoclonal antibody (CTJS-667) generated from the Mouse. The antibody can be used for WB, IP, IA.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-667 |
| Host Animal |
Mouse |
| Isotype |
IgG1 κ |
| Immunogen |
Human complement factor B |
| Species Reactivity |
Human |
| Applications |
WB; IP; IA |
| Application Notes |
WB: 1:50
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement Factor B Ba. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
Target
| Target Name |
Factor Ba |
| Alternative Names |
Complement Factor Ba; Complement Factor Ba fragment; Factor Ba fragment; CF Ba |
| Gene ID |
629 |
| UniProt ID |
P00751 |
Information
| Introduction |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
