Rabbit Anti-Mouse Collectin-11 Monoclonal Antibody (TJL-232) [Alexa Fluor 532](Cat#: CTMM-0322-JL2407)
This product is an Alexa Fluor 532 conjugated anti-Mouse Complement Collectin-11 Monoclonal antibody (TJL-232) generated from the Rabbit. The antibody can be used for ELISA.
Summary
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Specifications
Clonality |
Monoclonal |
Clone |
TJL-232 |
Host Animal |
Rabbit |
Isotype |
IgG |
Immunogen |
Recombinant Mouse CL-K1/COLEC11 |
Species Reactivity |
Mouse |
Applications |
ELISA |
Application Notes |
ELISA: 1:5000-1:10000 The optimal working dilutions should be determined by the end user. |
Specificity |
This antibody reacts with Mouse Complement Collectin-11. |
Purity |
≥95% as determined by SDS-PAGE |
Conjugation |
Alexa Fluor 532 |
Format |
Liquid |
Size |
0.1 ml |
Storage |
Store in dark at 4°C. Do Not Freeze. |
Type |
Primary Antibody |
Target
Target Name |
Collectin-11 |
Alternative Names |
Collectin Subfamily Member 11; Collectin Kidney Protein 1; Collectin K1; Collectin-11; CL-K1; Collectin Sub-Family Member 11; CL-K1-Iia; CL-K1-Iib; CL-K1-II; COLEC11; 3MC2; CLK1 |
Gene ID |
71693 |
UniProt ID |
Q3SXB8-1 |
Information
Introduction |
Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migRation of neural crest cells and other cell types during embryogenesis. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.