Rat Anti-Mouse C5aR1 Monoclonal Antibody (CTJS-762) [Alexa Fluor 647](Cat#: CTA-944)
This product is a conjugated anti-Mouse C5aR1 Monoclonal antibody (CTJS-762) generated from the Rat. The antibody can be used for FC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-762 |
| Host Animal |
Rat |
| Isotype |
IgG2b κ |
| Immunogen |
RBL-2H3 transfected cells expressing murine C5aR |
| Species Reactivity |
Mouse |
| Applications |
FC |
| Application Notes |
FC: 0.5 µg/10^6 cells
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Mouse C5aR1. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Alexa Fluor 647 |
| Format |
Liquid |
| Size |
25; 100 μg |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
C5aR1 |
| Alternative Names |
Complement C5a Receptor 1; C5AR; C5a Anaphylatoxin Chemotactic Receptor 1; Complement Component 5a Receptor 1; C5a-R; C5R1; CD88; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor 4; Complement Component 5 Receptor 1; C5a Anaphylatoxin Receptor; CD88 Antigen; C5AR1; C5aR |
| Gene ID |
12273 |
| UniProt ID |
P30993 |
Information
| Introduction |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
