Adiponectin Blocking Peptide-4(Cat#: CTD-164)
This product is a synthetic peptide that used for blocking the activity of human Adiponectin antibody.
Summary
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Specifications
Purity |
>85% |
Pack Size |
1 mg; 5 mg |
Format |
Lyophilized |
Conjugate |
Unconjugated |
Species Reactivity |
Human |
Applications |
Blocking |
Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
Introduction |
Adiponectin, also known as adipocyte complement-related protein, is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.