AP50 Functional Test Kit(Cat#: CTK-908)
This product is a functional test kit to determine the activity of lternative complement apathway based on the erythrocytes hemolysis assay. It is available for the sample of plasma or serum of several species, such as human,mouse, rat, guinea pig, bovine, hamster, swine, sheep, monkey. This kit also can be used to screen oe assess the pharmaceutical effect of complement therapeutic inhibitors or activators.
Summary
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Specifications
| Assay Type |
Complement Functional Assay |
| Species Reactivity |
Mul-species (human,mouse, rat, guinea pig, bovine, hamster, swine, sheep, monkey) |
| Applications |
Complement functional test |
| Storage |
Short-term storage at 4°C and long-term storage at -20°C. |
Information
| Introduction |
The AH50, similar to CH50, is used to represent the total complement activity, or screen the activation/deficiency of the alternative complement pathway. The alternative complement pathway can be activated by hydrolysis of C3 or by microbial polysaccharides and does not require immune complex formation. The membrane attack complex formed by the alternative complement pathway also can lyse the antibody-SRBC complex even if a deficiency of the classical complement pathway. But AH50 will be decreased due to hereditary or acquired deficiencies of the alternative pathway. The combination of CH50 and AH50 tests can be used for the identification of the specific pathway abnormality. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
