Creative Biolabs can be the partner of choice in the field of complement drug discovery, our extensive project experience has enabled us to build long-term relationships with the world's leading pharmaceutical and biotechnology companies.
Decay Accelerating Factor (DAF/CD55) Purification Protocol
CD55 has recently been defined as a ligand for an early activation marker on leukocytes (CD97). CD55 (decay accelerating factor; DAF) is also a GPI-anchored protein that is expressed on the surface of virtually all cells. It functions by dissociating the C3 convertases (C4bC2a and C3bBb) and consequently the C5 convertases into their parts, after which they are no longer able to reassociate.
Fig.1 Flow chart of decay accelerating factor (DAF/CD55) purification protocol. (Creative Biolabs)
Services and Product at Creative Biolabs
As a partner in drug discovery services, Creative Biolabs provides unique and specialized support for the entire drug discovery process. If you are looking for a quality solution that combines best practices in the field of complement drug discovery, please feel free to contact us.
Please note that our protocols are only for your reference!
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