This product is an ELISA kit for the determination of Human Complement C4BP in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Human Complement C4BP as low as 15.3 pg/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 15.3 pg/mL (31.2-2000 pg/mL) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | C4b Binding Protein |
Cross Reactivity | No significant cross-reactions have been observed between Human Complement C4BP and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | C4b-binding protein controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component. |