MBL-associated serine protease, also known as MASP, has been proven to be a mixture of two proteases: MASP-1 and MASP-2. MASP-1 is a multidomain serine protease that plays important roles in blood coagulation and can enhance complement activation of the related enzyme MASP-2. Studies have shown that MASP-2 efficiently cleaves both C4 and C2, while MASP-1 is only active on C2. In addition, MASP-1 cleaves a variety of substrates including fibrinogen and factor XIII, and is active in gelatin zymography. To help customers have deep research on MASP-1 and MASP-2, Creative Biolabs has developed novel protocols for the purification of MASP-1 and MASP-2. Please note that our protocols are only for your reference.
MASP-1 and MASP-2 Purification Protocol
Fig.1 Flow chart of the MASP-1 and MASP-2 purification protocol. (Creative Biolabs)
To fill the gaps in this field of the human complement system, scientists at Creative Biolabs has developed a variety of products and services for deep research. For customers' special project requirements, we can also offer fully customizable experimental design to expand beyond standard procedure.
Services and Product at Creative Biolabs
If you are interested in our products and services, please do not hesitate to contact us for more information.
Please note that our protocols are only for your reference!
For Research Use Only.
