Mouse Anti-Human CD11b Monoclonal Antibody (TJL-168) [Alexa Fluor 488](Cat#: CTMM-0322-JL1690)
This product is an Alexa Fluor 488 conjugated anti-Human Complement CD11b Monoclonal antibody (TJL-168) generated from the Mouse. The antibody can be used for Flow.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
TJL-168 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Species Reactivity |
Human |
| Applications |
Flow |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement CD11b. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Alexa Fluor 488 |
| Format |
Liquid |
| Size |
100 ul |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
CD11b |
| Alternative Names |
CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; complement receptor 3 |
| Gene ID |
3684 |
| UniProt ID |
P11233 |
Information
| Introduction |
The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, fibrinogen, and the C3 complement fragment, C3bi) to mediate phagocyte adhesion, migRation and ingestion of complement-opsonized particles |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
