This product is an Alexa Fluor 546 conjugated anti-Rat Complement C5b-9 complex Monoclonal antibody (TJL-64) generated from the Mouse. The antibody can be used for WB, IF, IHC, FCM.
Clonality | Monoclonal |
Clone | TJL-64 |
Host Animal | Mouse |
Isotype | IgG1 Kappa |
Immunogen | Purified Rat C5b-9 |
Species Reactivity | Rat |
Applications | WB; IF; IHC; FCM |
Application Notes | WB: 1:100-1:1000 IF: 1:50-1:500 IHC: 1:50-1:500 |
Specificity | This antibody reacts with Rat Complement C5b-9 complex. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Alexa Fluor 546 |
Format | Liquid |
Size | 200 µg |
Storage | Store in dark at 4°C. Do Not Freeze. |
Type | Primary Antibody |
Target Name | C5b-9 complex |
Alternative Names | Membrane attack complex; MAC; Terminal complement complex; TCC; scC5b-9 |
Introduction | C5b-9 complex is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. It is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Assembly of the MAC leads to pores that disrupt the cell membrane of target cells, leading to cell lysis and death. |