Rabbit Anti-Human Complement C4 Monoclonal Antibody (CTJS-63)(Cat#: CTA-099)
This product is an unconjugated anti-Human Complement C4 Monoclonal antibody (CTJS-63) generated from the Rabbit. The antibody can be used for IHC.
Summary
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Specifications
Clonality |
Monoclonal |
Clone |
CTJS-63 |
Host Animal |
Rabbit |
Isotype |
IgG |
Immunogen |
Peptide derived from internal sequence of human C4. |
Species Reactivity |
Human |
Applications |
IHC |
Application Notes |
IHC: 1:100 - 1:200 The optimal working dilutions should be determined by the end user. |
Specificity |
This antibody reacts with Human complement C4. |
Purity |
≥95% as determined by SDS-PAGE |
Format |
Liquid |
Size |
100 µL |
Storage |
4°C |
Type |
Primary Antibody |
Target
Target Name |
C4 |
Alternative Names |
Complement C4; Complement Component C4; Complement Component 4 ; C4 |
Gene ID |
720 |
UniProt ID |
P0C0L4 |
Information
Introduction |
Complement C4 is an important member in the complement cascade. Human C4 is a glycosylated protein originating from the human leukocyte antigen system. C4 is homologous to complement C3 and C5, sharing ~30% homology with them. Mature C4 is a trimer protein complex composed of three polypeptide chains: α chain, β chain, and γ chain, which provides a surface for interaction between the antigen-antibody complex and other complement components. Once the complement classical pathway or the lectin pathway were activated, the related activated proteases C1s or MASP-2 immediately cleave complement component 4 (C4) into two fragments C4a and C4b. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.