C4BP is a special glycoprotein that acts as a key regulator in the classical pathway as well as the lectin pathway. C4BP mediates inhibition of the classical
pathway of complement in a variety of ways by modulating C4b-mediated responses. First, C4BP acts as a co-factor in
the proteolytic inactivation of C4b for the serine protease Factor I, which is closely related to C4b inactivation.
Second, C4BP plays a critical role in preventing the production of the classical C3 convertase. More importantly,
C4BP promotes the natural decay of this enzyme complex. As a recognized leading expert in the field of complement, Creative Biolabs is always willing to share cutting-edge technology in this field with you. Here,
we provide a brief introduction to the functional assay procedure of C4BP.
C4BP Functional Analysis Protocol
The assay of C4BP is based on the ability of C4bp to serve as a cofactor for Factor I-mediated cleavage and
production of inactivated C4b.
Fig.1 Flow chart of C4BP
functional analysis protocol. (Creative Biolabs)
After decades of expansion and innovation, Creative Biolabs has accumulated rich experience in the
field of complement research. Our diverse services cover all aspects of the field of complement, from complement
antibody and inhibitor development to complement function testing to meet your unique needs. Moreover, a variety of
high-quality products can meet your different experimental needs. With our consolidated global resources, our
cost-effective complement services and products will provide you with a cutting-edge platform to exponentially
accelerate the research progress of your complement program.
Fig.1 Flow chart of C4BP
functional analysis protocol. (Creative Biolabs)
