C9 Purification Protocol

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C9 Purification Protocol

Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. C9, a single-chain plasma protein (molecular weight 69 kDa), binds the α-chain of C8 in the C5b-8 complex and undergoes a major conformational change from a globular, hydrophilic form to an elongated, amphipathic form which traverses the membrane and exacerbates membrane leakiness.

Flow chart of C9 purification protocol. Fig.1 Flow chart of C9 purification protocol. (Creative Biolabs)

Services and Products at Creative Biolabs

Creative Biolabs is a bio-CRO company with a long-term commitment to research and development of related technologies in the field of biomedical research. We have been assisting research institutes and pharmaceutical companies to design project plans. Through continuous efforts to improve expertise and platform building to help you achieve your research goals in the complement field, you can quickly drive your results. Please feel free to contact us to further communicate your research needs and we are happy to assist you.

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