Complement Factor B Blocking Peptide-1(Cat#: CTD-075)
This product is a synthetic peptide that used for blocking the activity of human Complement Factor B antibody.
Summary
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Specifications
| Sequence |
NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG |
| Purity |
>90% |
| Pack Size |
100 μg |
| Format |
Lyophilized |
| Conjugate |
Unconjugated |
| Species Reactivity |
Human |
| Applications |
Blocking; WB |
| Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
| Introduction |
Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
