Human Complement C5A Peptide(Cat#: CTD-055)
This product is a synthetic human complement C5A peptide with the sequence of YSFKDMQLGR.
Summary
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Specifications
| Sequence |
YSFKDMQLGR |
| Purity |
>95% |
| Pack Size |
1 mg; 5 mg; 10 mg |
| Format |
Lyophilized |
| Conjugate |
Unconjugated |
| Species Reactivity |
Human |
| Storage |
Short at 4°C for short term and at -20°C for long term. |
Information
| Introduction |
Complement C5a is the alpha chain released from cleavage of complement C5 protein, which plays an important role in chemotaxis. C5a is an effective chemoattractant, initiating accumulation of complement and phagocytic cells at sites of infection or recruitment of antigen-presenting cells to lymph nodes. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. White blood cells are activated by upregulation of integrin avidity, the lipoxygenase pathway and arachidonic acid metabolism. C5a also modulates the balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing the autoimmune response. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
