Zymosan is primarily composed of the highly cross-linked polysaccharides alpha-D-mannan, beta-D-glucan, and other minor polysaccharide polymers. This product has been pre-activated to develop its full complement-activating activity and is sold as a suspension in saline.
Application | Zymosan is used as an activator of the alternative pathway of complement and as a target for phagocytosis by PMN, macrophages and other phagocytic cells. It can be used to consume complement and generate all of the complement activation products such as C3a, C5a, SC5b-9, iC3b, Ba, Bb, etc. Zymosan will activate all three pathways of complement. |
Form | Frozen suspension |
Concentration | 1 x 109 zymosan particles/mL (10 mg/mL) |
Storage | Storage at -70°C. |