Among many candidate C1q receptors, two C1q receptors, cC1qR and gC1qR, have been widely reported. cC1qR was determined as a receptor for the collagen domain of C1q while gC1qR is a receptor specific for the globular head domain. Like C1q, these receptors also have a variety of specificities and functions. For example, cC1qR is part of the multiprotein-binding scavenger receptor complex CD91, of which the β chain serves as a special signaling protein. gC1qR is a common coreceptor with multiligand interaction and effector properties in diverse tissues. As an expert in the field of complement research, Creative Biolabs is willing to share methods for C1q receptor purification.
Purification Protocol for C1q Receptors
The two methods outlined here describe the isolation of two receptors respectively.
Fig.1 Flow chart of cC1qR purification protocol. (Creative Biolabs)
gC1qR was isolated by another approach. The simple process is described in the following flow chart:
Fig.2 Flow chart of gC1qR purification protocol. (Creative Biolabs)
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Please note that our protocols are only for your reference!
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