C5a-Mediated Cell Migration In Vivo Protocol

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C5a-Mediated Cell Migration In Vivo Protocol

C5a plays a crucial role in the inflammatory response and immune regulation. Most of the biological functions of C5a depend on binding and activating the corresponding receptor C5aR. Studies have revealed that C5aR activation is closely linked to the remodeling of the cytoskeleton, which leads to increased cell motility and ligand-specific cell migration. Here, we describe a protocol for C5a-mediated cell migration in vitro.

Flow chart of C5a-mediated cell migration in vivo protocol. Fig.1 Flow chart of C5a-mediated cell migration in vivo protocol. (Creative Biolabs)

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