The complement system occupies an irreplaceable position in the humoral immunity of mammals. As the vital enzymes of the complement cascade, C3 convertases and their proper regulation are critical for the protection of native tissues from complement-mediated destruction. Based on this, various complement modulators, such as factor H (FH), complement receptor 1 (CR1) and decay-accelerating factors prevent C3b opsonization by promoting the decay acceleration of C3 convertase. With rich experience in complement research, Creative Biolabs is committed to providing you with a one-stop solution as well as diversified products for complement research and drug development.
Decay-Accelerating Activity Assay Protocol
Here, we provide a brief introduction to the decay-accelerating activity assay by monitoring C3a production.
Fig.1 Flow chart of decay-accelerating activity assay. (Creative Biolabs)
With decades of complement research experience and an advanced technology platform, Creative Biolabs provides a customized solution for complement research. Our diverse range of analytical services ensures you get the desired results and a better interpretation of complement function, which contributes to the exploitation of promising new complement therapies. Furthermore, our high-quality complement products provide a favorable guarantee for your complement research projects. Our featured complement products are listed below:
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Please note that our protocols are only for your reference.
For Research Use Only.
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