siRNA, Anti-GIT1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76313WQ-2OMe)
The product SIRGT76313WQ-2OMe is a type of small interfering RNA (siRNA) that targets GIT1 gene and regulates the expression of gene. The siRNA interferes with the expression of GIT1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_014030.3 |
| Related Diseases | Progressive Myoclonus Epilepsy 7 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT77313WQ-2F | GIT1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT78313WQ-2MOE | GIT1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT79313WQ-LNA | GIT1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT91776WQ-2OMe | Git1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT92776WQ-2F | Git1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT93776WQ-2MOE | Git1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT94776WQ-LNA | Git1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT76313WQ-RB | GIT1 | Human | Ribo-modified | ||
| SIRGT91776WQ-RB | Git1 | Mouse | Ribo-modified | ||
| SIRGT77313WQ-BB | GIT1 | Human | Backbone-modified | ||
| SIRGT92776WQ-BB | Git1 | Mouse | Backbone-modified |
