Custom Production Solutions
Creative Biolabs delivers comprehensive custom production solutions that transform your gene therapy concepts into high-quality, research-ready materials. Our integrated platform combines state-of-the-art oligonucleotide synthesis capabilities with advanced viral vector production expertise, providing you with a complete suite of services to accelerate your gene therapy development. With decades of combined experience and cutting-edge technology platforms, we ensure that every custom project meets the highest standards of quality, purity, and functionality while adhering to your specific timeline and budget requirements.
Our Services
Custom Oligonucleotide Synthesis & Modification
Our oligonucleotide synthesis platform represents the pinnacle of precision and versatility in custom nucleic acid production. Utilizing advanced phosphoramidite chemistry and automated solid-phase synthesis technology, we deliver a comprehensive range of oligonucleotides from simple primers to complex therapeutic constructs. Our capabilities encompass unmodified and extensively modified oligonucleotides, including siRNA, miRNA, antisense oligonucleotides, and mRNA, with scales ranging from milligrams to kilograms. Each synthesis benefits from our extensive modification portfolio, featuring over 50 chemical modifications including 2'-modifications, backbone alterations, and specialized conjugations such as GalNAc and fluorescent labels. With rigorous quality control processes incorporating HPLC, mass spectrometry, and sequence verification, we consistently achieve purity levels exceeding 95% while maintaining exceptional batch-to-batch consistency for your most demanding applications.
Custom Viral Vector Production
Our viral vector production services provide reliable, scalable solutions for gene delivery across diverse research and therapeutic applications. We specialize in manufacturing a comprehensive range of viral vectors including Lentiviral, Adenoviral, Adeno-associated virus (AAV), Herpes Simplex virus, and Vaccinia viral vectors. Each production campaign leverages our established cell banking systems and optimized production protocols to ensure high titers and exceptional quality. Our multi-step purification strategies, ranging from density gradient ultracentrifugation to advanced chromatographic methods, are tailored to your specific downstream applications. Whether you require research-grade vectors for in vitro studies or highly purified preparations for in vivo applications, our flexible production systems and stringent quality control standards deliver viral vectors that meet your exact specifications while maintaining safety and efficacy throughout the development process.
Why Choose Us
- Technical Excellence: Our integrated production facilities combine cutting-edge synthesis platforms with advanced bioprocessing capabilities, enabling seamless execution of complex projects requiring both oligonucleotides and viral vectors.
- Quality Assurance: Every product undergoes comprehensive analytical characterization and quality control testing, supported by detailed documentation and certificates of analysis that ensure full traceability and regulatory compliance.
- Flexible Scale: From proof-of-concept studies to large-scale production, our scalable processes adapt to your project requirements while maintaining consistent quality across all production scales.
- Expert Support: Our dedicated project management team and technical specialists provide end-to-end support, from initial consultation and design optimization to final delivery and technical assistance.
- Streamlined Timeline: Integrated production capabilities and optimized workflows enable accelerated timelines without compromising quality, helping you meet critical research and development milestones.
