Custom Research & Development
Creative Biolabs stands at the forefront of nucleic acid-based therapeutic development, offering comprehensive services that span the entire spectrum of RNA and DNA technologies. Our integrated platform combines cutting-edge synthesis capabilities with advanced screening and validation services, providing researchers and pharmaceutical companies with complete solutions for nucleic acid drug discovery and development. From novel circular RNAs to established antisense oligonucleotides and siRNA therapeutics, our expertise covers all major categories of nucleic acid therapeutics, supported by state-of-the-art facilities and decades of accumulated technical knowledge.
Our Services
Transform your nucleic acid-based therapeutic concepts into reality through our integrated development platform that encompasses all major RNA and DNA modalities. Our comprehensive nucleic acid services unite three core capabilities: innovative circular RNA (circRNA) technologies for next-generation stable therapeutics, complete antisense oligonucleotide (ASO) development from design to validation, and sophisticated siRNA screening for target discovery and validation. Each service leverages our state-of-the-art synthesis facilities, advanced modification chemistry, and extensive analytical capabilities to deliver high-quality nucleic acids optimized for your specific applications. Whether you're exploring the exceptional stability of circRNAs for sustained protein expression, developing ASOs with enhanced targeting through antibody conjugation, or conducting genome-wide siRNA screens to identify novel therapeutic targets, our integrated approach ensures seamless progression from initial concept through preclinical validation.
Custom Viral Vector Development
Harness the power of viral-mediated gene delivery with our comprehensive custom viral vector development services, designed to meet the unique requirements of your gene therapy research. Our expertise encompasses the complete spectrum of viral vector systems, from widely-used lentiviral and adeno-associated virus (AAV) platforms to specialized vectors including herpes simplex virus, vaccinia virus, and baculovirus systems. Each vector type offers distinct advantages—whether it's the long-term expression capability of integrating lentiviral vectors, the low immunogenicity of AAV, or the neurotropic properties of HSV for nervous system targeting. Our custom development process includes vector design optimization, plasmid construction, molecular engineering for enhanced tropism, and scalable production from research to clinical grade. With advanced directed evolution techniques and proprietary engineering approaches, we create vectors with improved safety profiles, enhanced transduction efficiency, and tissue-specific targeting capabilities tailored to your therapeutic goals.
Our Custom R&D Approach
- Collaborative Partnership Model: We begin every project with in-depth consultation to understand your specific research objectives, technical requirements, and development timeline, creating customized strategies that align with your goals while leveraging our technical expertise.
- Integrated Technology Platform: Our unified R&D infrastructure enables seamless integration between viral vector and nucleic acid technologies, allowing for innovative combination approaches and streamlined development workflows that reduce time and costs.
- Scalable Solutions: From proof-of-concept studies to large-scale production, our flexible manufacturing capabilities adapt to your project's evolving needs, ensuring consistent quality as you progress from research through preclinical development.
- Quality-Driven Process: Every custom project benefits from our rigorous quality control systems, comprehensive analytical characterization, and detailed documentation protocols that meet the highest industry standards for research and regulatory compliance.
- Expert Technical Support: Our multidisciplinary team of molecular biologists, virologists, and nucleic acid chemists provides continuous technical guidance, troubleshooting support, and strategic insights throughout your project lifecycle.
Why Choose Us
- Comprehensive Capabilities: Access the full spectrum of gene therapy technologies under one roof, from traditional viral vectors to emerging nucleic acid therapeutics, enabling innovative therapeutic approaches and reducing vendor complexity.
- Proven Expertise: Leverage decades of collective experience in gene therapy development, supported by successful delivery of hundreds of custom projects across diverse therapeutic areas and technical challenges.
- Innovation-Focused: Stay at the forefront of gene therapy advancement through our commitment to integrating new technologies, developing novel approaches, and continuously improving our technical capabilities.
- Flexible Engagement Models: Choose from complete end-to-end development partnerships or targeted support for specific project phases, with customizable service packages that match your budget and timeline requirements.
- Accelerated Timelines: Benefit from optimized workflows, parallel processing capabilities, and experienced project management that consistently deliver results faster than traditional development approaches.
