siRNA, Anti-IRAK4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76403WQ-2OMe)

The product SIRGT76403WQ-2OMe is a type of small interfering RNA (siRNA) that targets IRAK4 gene and regulates the expression of gene. The siRNA interferes with the expression of IRAK4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016123.3
Alternative Names IPD1; IRAK-4; NY-REN-64; REN64
Related Diseases Irak4 Deficiency
Purification HPLC
Target Gene
Gene ID 51135
Uniprot ID Q9NWZ3
Sub Cat Target Species Modification Scale  
SIRGT77403WQ-2F IRAK4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78403WQ-2MOE IRAK4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79403WQ-LNA IRAK4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76403WQ-RB IRAK4 Human Ribo-modified Inquiry
SIRGT77403WQ-BB IRAK4 Human Backbone-modified Inquiry

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