siRNA, Anti-KCNIP1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76411WQ-2OMe)

The product SIRGT76411WQ-2OMe is a type of small interfering RNA (siRNA) that targets KCNIP1 gene and regulates the expression of gene. The siRNA interferes with the expression of KCNIP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014592.3
Alternative Names KCHIP1; VABP
Related Diseases Episodic Ataxia, Type 4
Purification HPLC
Target Gene
Gene ID 30820
Uniprot ID Q9NZI2
Sub Cat Target Species Modification Scale  
SIRGT77411WQ-2F KCNIP1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78411WQ-2MOE KCNIP1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79411WQ-LNA KCNIP1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76411WQ-RB KCNIP1 Human Ribo-modified Inquiry
SIRGT77411WQ-BB KCNIP1 Human Backbone-modified Inquiry

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