siRNA, Anti-KCNK4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76414WQ-2OMe)

The product SIRGT76414WQ-2OMe is a type of small interfering RNA (siRNA) that targets KCNK4 gene and regulates the expression of gene. The siRNA interferes with the expression of KCNK4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_033310.2
Alternative Names K2p4.1; TRAAK; TRAAK1
Related Diseases Gingival Overgrowth Syndrome
Purification HPLC
Target Gene
Gene ID 50801
Uniprot ID Q9NYG8
Sub Cat Target Species Modification Scale  
SIRGT77414WQ-2F KCNK4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78414WQ-2MOE KCNK4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79414WQ-LNA KCNK4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76414WQ-RB KCNK4 Human Ribo-modified Inquiry
SIRGT77414WQ-BB KCNK4 Human Backbone-modified Inquiry

Related Products