siRNA, Anti-SLIRP, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT74766WQ-LNA)

The product SIRGT74766WQ-LNA is a type of small interfering RNA (siRNA) that targets SLIRP gene and regulates the expression of gene. The siRNA interferes with the expression of SLIRP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_031210.5
Alternative Names C14orf156; DC50; PD04872
Related Diseases Leigh Syndrome
Purification HPLC
Target Gene
Gene ID 81892
Uniprot ID Q9GZT3
Sub Cat Target Species Modification Scale  
SIRGT71766WQ-2OMe SLIRP Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT72766WQ-2F SLIRP Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73766WQ-2MOE SLIRP Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT71766WQ-RB SLIRP Human Ribo-modified Inquiry
SIRGT72766WQ-BB SLIRP Human Backbone-modified Inquiry

Related Products