siRNA, Anti-Gucy1b3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT96943WQ-2OMe)

The product SIRGT96943WQ-2OMe is a type of small interfering RNA (siRNA) that targets Gucy1b3 gene and regulates the expression of gene. The siRNA interferes with the expression of Gucy1b3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_017469.4
Alternative Names GC-S-beta-1; GCbeta1
Related Diseases Alzheimer's Disease
Purification HPLC
Target Gene
Gene ID 54195
Uniprot ID O54865
Sub Cat Target Species Modification Scale  
SIRGT97943WQ-2F Gucy1b3 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT98943WQ-2MOE Gucy1b3 Mouse 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT99943WQ-LNA Gucy1b3 Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT96943WQ-RB Gucy1b3 Mouse Ribo-modified Inquiry
SIRGT97943WQ-BB Gucy1b3 Mouse Backbone-modified Inquiry

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