siRNA, Anti-Kiz, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT97141WQ-2F)
The product SIRGT97141WQ-2F is a type of small interfering RNA (siRNA) that targets Kiz gene and regulates the expression of gene. The siRNA interferes with the expression of Kiz gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001033298.3 |
| Alternative Names | Gm114; Ncrna00153; Plk1s1 |
| Related Diseases | Retinitis Pigmentosa 69 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT41969WQ-2OMe | KIZ | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT42969WQ-2F | KIZ | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT43969WQ-2MOE | KIZ | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT44969WQ-LNA | KIZ | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT98141WQ-2MOE | Kiz | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99141WQ-LNA | Kiz | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT41969WQ-RB | KIZ | Human | Ribo-modified | ||
| SIRGT96141WQ-RB | Kiz | Mouse | Ribo-modified |
