siRNA, Anti-ANGPTL6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46683WQ-2OMe)

The product SIRGT46683WQ-2OMe is a type of small interfering RNA (siRNA) that targets ANGPTL6 gene and regulates the expression of gene. The siRNA interferes with the expression of ANGPTL6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001321411.1
Alternative Names AGF; ARP5
Related Diseases Familial Cerebral Saccular Aneurysm
Purification HPLC
Target Gene
Gene ID 83854
Uniprot ID Q8NI99
Sub Cat Target Species Modification Scale  
SIRGT47683WQ-2F ANGPTL6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48683WQ-2MOE ANGPTL6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49683WQ-LNA ANGPTL6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46683WQ-RB ANGPTL6 Human Ribo-modified Inquiry
SIRGT47683WQ-BB ANGPTL6 Human Backbone-modified Inquiry

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