siRNA, Anti-APOA4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01224WQ-2OMe)

The product SIRGT01224WQ-2OMe is a type of small interfering RNA (siRNA) that targets APOA4 gene and regulates the expression of gene. The siRNA interferes with the expression of APOA4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000482.3
Related Diseases Carotenemia, Familial Hypercholesterolemia
Purification HPLC
Target Gene
Gene ID 337
Uniprot ID P06727
Sub Cat Target Species Modification Scale  
SIRGT02224WQ-2F APOA4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03224WQ-2MOE APOA4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04224WQ-LNA APOA4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01224WQ-RB APOA4 Human Ribo-modified Inquiry
SIRGT02224WQ-BB APOA4 Human Backbone-modified Inquiry

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